PT  - JOURNAL ARTICLE
AU  - Scherer, Philip M.
AU  - Chen, Delphine L.
TI  - Imaging Pulmonary Inflammation
AID  - 10.2967/jnumed.115.157438
DP  - 2016 Nov 01
TA  - Journal of Nuclear Medicine
PG  - 1764--1770
VI  - 57
IP  - 11
4099  - http://jnm.snmjournals.org/content/57/11/1764.short
4100  - http://jnm.snmjournals.org/content/57/11/1764.full
SO  - J Nucl Med2016 Nov 01; 57
AB  - Lung inflammatory diseases contribute significantly to the socioeconomic burden of disease. Yet very few new, effective therapies for respiratory disease have been approved for use. A major contributing factor is the lack of biomarkers that can accurately quantify the lung inflammatory burden and can be used to understand the contribution of lung inflammation to loss in lung function. Molecular imaging approaches can detect and quantify the recruitment and activation of specific immune cells in lung inflammation. We review the clinical techniques used to image lung inflammation, provide an overview of clinical and emerging PET techniques for quantifying lung inflammation, and discuss potential clinical applications.