RT Journal Article SR Electronic T1 Evaluation of Prostate Cancer with 11C-Acetate PET/CT JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 30S OP 37S DO 10.2967/jnumed.115.169599 VO 57 IS Supplement 3 A1 Claudio Spick A1 Ken Herrmann A1 Johannes Czernin YR 2016 UL http://jnm.snmjournals.org/content/57/Supplement_3/30S.abstract AB In this article, we will first describe the metabolic fate of 11C-acetate; then discuss its biodistribution in health and disease; and subsequently focus on its key clinical applications, the detection and localization of prostate cancer tissue in patients with primary or recurrent disease. Finally, we will discuss the potential role of 11C-acetate in the context of other prostate cancer imaging probes and non–radionuclide-based imaging approaches.