RT Journal Article SR Electronic T1 Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 144 OP 150 DO 10.2967/jnumed.115.158915 VO 57 IS 1 A1 Rosenthal, Eben L. A1 Warram, Jason M. A1 de Boer, Esther A1 Basilion, James P. A1 Biel, Merrill A. A1 Bogyo, Matthew A1 Bouvet, Michael A1 Brigman, Brian E. A1 Colson, Yolonda L. A1 DeMeester, Steven R. A1 Gurtner, Geoffrey C. A1 Ishizawa, Takeaki A1 Jacobs, Paula M. A1 Keereweer, Stijn A1 Liao, Joseph C. A1 Nguyen, Quyen T. A1 Olson, James M. A1 Paulsen, Keith D. A1 Rieves, Dwaine A1 Sumer, Baran D. A1 Tweedle, Michael F. A1 Vahrmeijer, Alexander L. A1 Weichert, Jamey P. A1 Wilson, Brian C. A1 Zenn, Michael R. A1 Zinn, Kurt R. A1 van Dam, Gooitzen M. YR 2016 UL http://jnm.snmjournals.org/content/57/1/144.abstract AB Navigation with fluorescence guidance has emerged in the last decade as a promising strategy to improve the efficacy of oncologic surgery. To achieve routine clinical use, the onus is on the surgical community to objectively assess the value of this technique. This assessment may facilitate both Food and Drug Administration approval of new optical imaging agents and reimbursement for the imaging procedures. It is critical to characterize fluorescence-guided procedural benefits over existing practices and to elucidate both the costs and the safety risks. This report is the result of a meeting of the International Society of Image Guided Surgery (www.isigs.org) on February 6, 2015, in Miami, Florida, and reflects a consensus of the participants’ opinions. Our objective was to critically evaluate the imaging platform technology and optical imaging agents and to make recommendations for successful clinical trial development of this highly promising approach in oncologic surgery.