PT  - JOURNAL ARTICLE
AU  - Satz, Stanley
TI  - Clinical application of O (2-Fluorine-18-Fluoroethyl)-L-tyrosine PET for diagnosis of juvenile pilocytic astrocytoma and medulloblastoma in pediatric patients
DP  - 2015 May 01
TA  - Journal of Nuclear Medicine
PG  - 1702--1702
VI  - 56
IP  - supplement 3
4099  - http://jnm.snmjournals.org/content/56/supplement_3/1702.short
4100  - http://jnm.snmjournals.org/content/56/supplement_3/1702.full
SO  - J Nucl Med2015 May 01; 56
AB  - 1702 Objectives O(2-Fluorine-18-Fluoroethyl)-L-Tyrosine (F-18-FET) PET may be used for diagnosis of juvenile pilocytic astrocytoma and medulloblastoma in pediatric patients. The objective was to gain experience in the diagnosis of these rare pediatric diseases.Methods Twenty patients were scanned with F-18-FET-PET and were analyzed. Maximum and mean tumor to brain ratios were determined 20 to 45 minutes after injection. Diagnostic accuracy was assessed using histology or clinical course.Results In tumors, sensitivity was 80%. Specificity was 70%. Positive predictive value was 86%Conclusions These findings suggest that F-18-FET can add information for decisionmaking in patients with pediatric brain tumors.Research Support Advanced Imaging Projects, LLC.