RT Journal Article SR Electronic T1 Correlation between 18F-Fluorocholine PET/CT scan and other clinical diagnostic parameters in prostate cancer patients JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1445 OP 1445 VO 56 IS supplement 3 A1 Anbalagan Kannivelu A1 Xuexian Yan A1 Kelvin Loke A1 David Ng YR 2015 UL http://jnm.snmjournals.org/content/56/supplement_3/1445.abstract AB 1445 Objectives The aim of the study is to determine whether or not 18F-Fluorocholine PET/CT (FCH PET/CT) scan is useful in the evaluation of prostatic carcinoma patients and supports other clinical (biochemical and histological) diagnostic criteria.Methods Over 18 months’ period, 45 consecutive patients of our hospital were selected retrospectively who underwent FCH PET/CT scan for the evaluation of prostatic carcinoma. Clinically they were considered positive when they had raising trend of PSA or histologically proven malignancy or both, and they were considered clinically negative when they did not have either. The FCH PET/CT scan findings were divided into three categories, (1) local disease: prostatic and extracapsular involvement, (2) nodal disease: pelvic and paraaortic nodes involvement, (3) distal metastases: bones and lungs. The FCH PET/CT scan findings were considered positive if at least one of them was positive. FCH PET/CT scans and clinical results were compared and analysed for correlation.Results In our study comprising 45 patients, 42 patients were clinically positive and three patients were clinically negative. In the clinically positive group (n=42), 39 patients' FCH PET/CT scans were positive and three patients' FCH PET/CT scans were equivocal or negative. In the clinically negative group (n=3), two patients' FCH PET/CT scans were negative and one patient's FCT PET/CT scan was equivocal. Thus there was a good correlation between findings of FCH PET/CT scans and clinical parameters in 41 out 45 patients, about 91%. The sensitivity of FCH PET/CT scan was 97.5% with positive predictive value of 93% and negative predictive value of 66.6%.Conclusions Our study demonstrated that the FCH PET/CT scan is a sensitive test to diagnose prostate carcinoma, supports clinical diagnostic parameters and can be used as an imaging tool for better disease localization.