PT - JOURNAL ARTICLE AU - Frederic H. Fahey AU - Henry Hee-Seong Bom AU - Arturo Chiti AU - Yun Young Choi AU - Gang Huang AU - Michael Lassmann AU - Norman Laurin AU - Fernando Mut AU - Rodolfo Nuñez-Miller AU - Darin O’Keeffe AU - Prasanta Pradhan AU - Andrew M. Scott AU - Shaoli Song AU - Nischal Soni AU - Mayuki Uchiyama AU - Luis Vargas TI - Standardization of Administered Activities in Pediatric Nuclear Medicine: A Report of the First Nuclear Medicine Global Initiative Project, Part 1—Statement of the Issue and a Review of Available Resources AID - 10.2967/jnumed.114.152249 DP - 2015 Apr 01 TA - Journal of Nuclear Medicine PG - 646--651 VI - 56 IP - 4 4099 - http://jnm.snmjournals.org/content/56/4/646.short 4100 - http://jnm.snmjournals.org/content/56/4/646.full SO - J Nucl Med2015 Apr 01; 56 AB - The Nuclear Medicine Global Initiative (NMGI) was formed in 2012 and consists of 13 international organizations with direct involvement in nuclear medicine. The underlying objectives of the NMGI were to promote human health by advancing the field of nuclear medicine and molecular imaging, encourage global collaboration in education, and harmonize procedure guidelines and other policies that ultimately lead to improvements in quality and safety in the field throughout the world. For its first project, the NMGI decided to consider the issues involved in the standardization of administered activities in pediatric nuclear medicine. This article presents part 1 of the final report of this initial project of the NMGI. It provides a review of the value of pediatric nuclear medicine, the current understanding of the carcinogenic risk of radiation as it pertains to the administration of radiopharmaceuticals in children, and the application of dosimetric models in children. A listing of pertinent educational and reference resources available in print and online is also provided. The forthcoming part 2 report will discuss current standards for administered activities in children and adolescents that have been developed by various organizations and an evaluation of the current practice of pediatric nuclear medicine specifically with regard to administered activities as determined by an international survey of nuclear medicine clinics and centers. Lastly, the part 2 report will recommend a path forward toward global standardization of the administration of radiopharmaceuticals in children.