RT Journal Article
SR Electronic
T1 The effect of additional delayed images for detection of peritoneal implants with (18)F-fluorodeoxyglucose (FDG) PET/CT
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1336
OP 1336
VO 53
IS supplement 1
A1 Sanli, Yasemin
A1 Kuyumcu, Serkan
A1 Yilmaz, Ebru
A1 Ozkan, Zeynep
A1 Gungor, Funda
A1 Turkmen, Cuneyt
A1 Unal, Seher
A1 Iyibozkurt, Cem
YR 2012
UL http://jnm.snmjournals.org/content/53/supplement_1/1336.abstract
AB 1336 Objectives To analyze the potential effect of (18)F-fluorodeoxyglucose (FDG) PET/CT using additional delayed images for the detection of peritoneal implants in recurrent suspected ovarian cancer patients. Methods The present study retrospectively included 27 patients (mean age: 54.1±10.6 years) with clinical or radiological suspicion of recurrent disease. Patients without peritoneal implants did not included to the study. Patients were evaluated in 3 groups according to their peritoneal implant size as; 0.5-1 cm (Group 1), 1-2 cm (Group2) and > 2 cm (Group 3). A whole body PET/CT scan was performed at 60 min (standard images) and after 2 hr (delayed images) post-injection of 14.1±3.8 mCi of (18)F-FDG. Visual and quantitative SUV analyses of PET/CT findings were performed. Results 16 patients in Group 1 were detected to have same lesions in early and delayed images; whereas 24 and 25 patients were detected peritoneal implants in group 2 with early and delayed images, respectively. In Group 2, 69 and 71 lesions were detected in early and late images, respectively. Meanwhile, 15 and 17 patients were detected to have peritoneal implants in Group 3 in early and delayed images, respectively. In this group, 46 and 58 lesions were detected in early and delayed images, respectively. All lesions were demonstrated to have increased FDG uptake in delayed images. The SUV max values of the lesions seen in early images were increased from 9.3±4.7 to 11.4±5.6 (p< 0.05) in delayed images. Conclusions The present study revealed that more peritoneal implants may be detected especially in patients with peritoneal implants < 1 cm with delayed images