PT  - JOURNAL ARTICLE
AU  - Patel, Chetan
AU  - Singh, Harmandeep
AU  - Sharma, Gautam
AU  - Naik, Nitish
AU  - Singla, Suhas
AU  - Malhotra, Arun
TI  - Assessment of left ventricular function and synchrony using equilibrium radionuclide angiography in patients with right ventricular outflow tract and apical pacing: One year follow up study
DP  - 2012 May 01
TA  - Journal of Nuclear Medicine
PG  - 1842--1842
VI  - 53
IP  - supplement 1
4099  - http://jnm.snmjournals.org/content/53/supplement_1/1842.short
4100  - http://jnm.snmjournals.org/content/53/supplement_1/1842.full
SO  - J Nucl Med2012 May 01; 53
AB  - 1842 Objectives Chronic dyssynchronous activation of left ventricle (LV) during right ventricular apical pacing (RVA) can lead to a decline in LV function. Right ventricular outflow tract (RVOT) pacing can lead to more physiological and synchronous activation of the ventricles. We used equilibrium radionuclide angiography (ERNA) to assess LV function and synchrony in patients with RVOT and RVA pacing over short term follow up. Methods Fifty one patients who underwent permanent pacemaker implantation and had normal LV function were prospectively included. Twenty nine patients had pacemaker lead positioned at RVOT site and 22 at the RVA site. All patients underwent ERNA under forced cardiac pacing at rate of 100/minute. Studies were performed within 2 week post pacemaker implantation and at 12 month follow up. Standard deviation of LV mean phase angle (SD LV mPA) expressed in degrees, which was derived by Fourier first harmonic analysis of phase images to quantify left intraventricular synchrony and LV ejection fraction (LVEF) were evaluated. Paced QRS duration (pQRSd) was obtained for all patients. Results No significant difference was observed between two groups with regards to indication (p 0.894) and percentage of ventricular pacing (p 0.352). pQRSd was significantly longer in RVA group than RVOT group (p 0.05). There was no statistically significant difference between RVOT and RVA groups at baseline with respect to LVEF (56.2 ± 5.47% vs. 55 ± 5.89%; p 0.474) and SD LV mPA (11.8 ± 5.26° vs. 12.9 ± 4.94°; p 0.386). Similarly, no significant difference was observed between the RVOT and RVA groups with respect to LVEF (53.6 ± 7.68% vs. 53.3 ± 7.01%; p 0.869) and SD LV mPA (12.6 ± 4.73° vs. 13.3 ± 6.22°; p 0.656) at 12 month follow up. Conclusions No significant difference was observed between RVOT & RVA group with regard to left ventricular function & synchrony at one year follow up