RT Journal Article
SR Electronic
T1 PET/contrast-enhanced CT detection of incidental colonic 18F-FDG uptake: Correlation with uptake patterns combined with CT findings and histopathology
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1818
OP 1818
VO 52
IS supplement 1
A1 Seo, Hyo Jung
A1 Kang, Won Jun
A1 Kim, Hyun Jeong
A1 Choi, Yun Jung
A1 Yun, Mijin
A1 Lee, Jong Doo
YR 2011
UL http://jnm.snmjournals.org/content/52/supplement_1/1818.abstract
AB 1818 Objectives To evaluate the incidental colonic FDG uptake in the patients without colorectal carcinoma who underwent PET/contrast-enhanced CT for other purpose, FDG uptake patterns combined with contrast-enhanced CT findings are compared with histopathology. Methods The files of 8,855 patients referred for 18F-FDG PET/contrast-enhanced CT were retrospectively reviewed. The patients showing incidental FDG uptake without colorectal cancer history were selected. Limited subjects who underwent FDG PET/contrast-enhanced CT and colonoscopy within 6 months were evaluated to confirm histopathology. Subgroups were classified by focal or diffuse uptake, and these groups were analyzed by histopathologic type and contrast-enhanced CT findings. Results Fifty nine of the subjects demonstrated 43 focal uptake and 16 diffuse uptake in colon incidentally. Contrast-enhanced CT findings revealed the mass, wall enhancement or wall thickening in the 31 cases and histopathologic confirmation through follow up colonoscopy determined 11 adenocarcinomas, 16 adenomas, and 4 benigns. Whereas, in the no mass lesion on the contrast-enhanced CT, histopathologic results showed that no adenocarcinoma, 7 adenoma and 5 benign. However, in sixteen cases showing diffuse colon, 8 cases showing mass lesions on the contrast-enhanced CT was classified by 2 adenocarcinomas, 1 adenoma, and 5 benigns, and 8 cases without mass lesion was divided by 1 adenocarcinoma, 4 adenomas, and 3 benigns. Conclusions Incidental FDG uptake evaluation is very important in most patients. Mass lesions detected by contrast-enhanced CT represented cancerous lesion rather than benign lesions. These findings should help to guide the follow up procedure and treatment in the patients with incidental colon FDG uptake