RT Journal Article
SR Electronic
T1 Comparison of contemporaneous left ventricular ejection fraction (LVEF) obtained from standard gated cardiac blood pool scans (GCBPS) and Tl-201 gated myocardial perfusion scans (MPS) using a novel solid state cardiac camera
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1156
OP 1156
VO 52
IS supplement 1
A1 Kenneth Yap
A1 Martin Cherk
A1 Michael Kelly
A1 Bruce Van Every
A1 Catherine McGrath
A1 Victor Kalff
YR 2011
UL http://jnm.snmjournals.org/content/52/supplement_1/1156.abstract
AB 1156 Objectives There is limited data on the concordance of LVEF obtained via ultrafast solid state cardiac cameras (UFC) and GCBPS. This study examined the agreement of LVEF measured during the rest component of stress-rest Tl-201 MPS using UFC (GE Discovery NM 530c) and GCBPS. Methods Consecutive patients referred for Tl-201 MPS and GCBPS using Tc-99m for routine clinical management of known or potential ischaemic heart disease, were enrolled. Following stress myocardial perfusion imaging (0.8 MBq/kg Tl-201) in 37 patients, 8 minute rest studies following further reinjection of 15 MBq of Tl-201were needed in 30 patients. Automated LVEF measurements were obtained using 8 frame gated MPS via ECToolbox and GE in-house software (Myovation) on the UFC. Immediately following rest MPS, LVEF measurements were obtained using 16 frame planar GCBPS via EF Analysis on the GE Optima NX, Discovery VH or Millennium cameras. All LVEFs were processed independently by 2 experienced operators. Pearson’s correlation coefficients (R value) were used to compare the different methods of calculating LVEF and interobserver variability. Conclusions LVEF obtained by ECT or Myovation demonstrate significant correlation with GCBPS. But ECT showed significant overestimation while Myovation underestimated low LVEF & overestimated high LVEF. LVEF measurement by any of these techniques is not interchangeable in clinical practice