RT Journal Article
SR Electronic
T1 FDG manual injection verses infusion system: A comparison of dose precision and extravasation
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 2031
OP 2031
VO 50
IS supplement 2
A1 Krumrey, Sarah
A1 Frye, Ross
A1 Tran, Isaac
A1 Yost, Penny
A1 Nguyen, Nghi
A1 Osman, Medhat
YR 2009
UL http://jnm.snmjournals.org/content/50/supplement_2/2031.abstract
AB 2031 Objectives The MEDRAD Intego™ PET Infusion System (Intego) is designed to deliver a more patient-specific FDG dose. We evaluated the precision of the FDG dose delivery and the frequency of extravasations when using the Intego compared to the standard manual injection. Methods The Intego is a lead-shielded mobile cart equipped with a dose calibrator and multi-dose vial of F-18 FDG. Patient-specific dose is measured and automatically infused into the patient once venous access is available. This system is designed to measure, infuse, and flush the FDG while providing additional shielding to technologists. In our PET center, we routinely record residual remaining activity for each FDG injection and acquire whole-body “head to toe” axial co-scan range for all cancer cases. Residual remaining activity and frequency of extravasations for the 98 patients injected using the Intego system were compared to another 98 patients injected manually immediately prior to starting the Intego. Results Average syringe residual activity per patient was 0.047mCi for the Intego and 0.25mCi for the manual technique. Frequency of extravasations was 3/98 (3%) for the Intego and 9/98 (9%) for the manual injection. Compared to the manual injection, the Intego system resulted in reducing average residual activity by 81% and frequency of extravasations by 67%. Conclusions Initial utilization of Intego in our PET center was successful, resulting in a more precise FDG dose delivery and fewer extravasations. Further work is planned to evaluate workflow, cost analysis, and radiation exposure and overall pros and cons of the Intego PET infusion system.