RT Journal Article
SR Electronic
T1 Partial volume effect (PVE) correction in SPECT during or post reconstruction: A comparison study
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1498
OP 1498
VO 50
IS supplement 2
A1 Lefteris Livieratos
A1 Adrien Le Pogam
A1 Nicolas Boussion
A1 Catherine Cheze-Le Rest
A1 Dimitris Visvikis
YR 2009
UL http://jnm.snmjournals.org/content/50/supplement_2/1498.abstract
AB 1498 Objectives Reconstruction based resolution recovery has been recently made widely available in clinical systems. In this study we compared the PHILIPS ASTONISHTM with a post-reconstruction deconvolution algorithm for PVE correction in SPECT. Methods The Philips ASTONISHTM reconstruction algorithm is based on 3D-OSEM with built-in corrections for resolution recovery (incorporating a depth dependent resolution model), scatter and attenuation correction. The post-processing algorithms were based on iterative deconvolution using the Lucy-Richardson and Van-Cittert algorithms. Wavelet and Curvelet based denoising were incorporated into the iteration process in order to eliminate the noise observed in deconvolution methods. Reconstruction based and post-processing approaches were compared on both a 99mTc SPECT/CT acquisition of the IEC phantom as well as clinical bone SPECT studies. Corrected images were compared in qualitative and quantitative terms with those reconstructed using a standard OSEM technique with attenuation and scatter correction. Results The post processing deconvolution algorithms with a wavelet/curvelet regularization showed similar or slightly better results compared to the ASTONISHTM reconstruction approach in terms of quantitative accuracy in the different spheres of the phantom. Furthermore, profile plots through the spheres indicate that the Lucy-Richardson algorithm leads to results close to ASTONISHTM. The phantom results were confirmed by the patient images obtained with the two different approaches. Conclusions A comparison of reconstruction based and post-processing deconvolution based approaches for PVE correction in SPECT show similar levels of qualitative and quantitative accuracy improvements.