RT Journal Article
SR Electronic
T1 Relationship between focal anal uptake and hemorrhoid in the FDG PET-CT
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1736
OP 1736
VO 50
IS supplement 2
A1 Kim, Young Chul
A1 Park, Eun Kyung
A1 Han, You Mie
A1 Choe, Jae Gol
YR 2009
UL http://jnm.snmjournals.org/content/50/supplement_2/1736.abstract
AB 1736 Objectives Incidental bowel uptakes in FDG PET-CT have been studied enough. But few studies have evaluated the clinical significance of incidental anal uptakes. The purpose of this study is to evaluate whether focal anal uptakes are meaningful findings of hemorrhoids. Methods Consecutive 1113 patients performed both FDG PET-CT and colonofibroscopy for cancer screening, diagnosis and follow up. FDG PET-CT was analyzed with visual assessment for focal uptake in the anus and with semi-quantitative analysis for standardized uptake values. Anal FDG uptakes distinguished from adjacent tissue at maximal intensity projection, sagittal and coronal images is considered focal anal uptake. Colonofibroscopy revealed existence of hemorrhoids visually. Statistical analysis was done between two groups; Group 1 was patients diagnosed with hemorrhoids in the colonofibroscopy and group 2 was age- and sex-matched control group with no evidence of anal diseases in the colonofibroscopy. Results 53 patients were diagnosed as hemorrhoids with colonofibroscopy (group 1). In group 1, 13 patients showed focal FDG uptake in the anus (SUV=3.7±0.76). But only 4 patients of group 2 (total 53 patients) show focal anal uptake (SUV=3.1±0.86). There are significant difference in the distributions of focal anal uptakes between group 1 and 2 (p<0.05), but not in standardized uptake values. Conclusions Hemorrhoids have a significant correlation with focal anal uptake in visual assessment, not in semi-quantitative analysis using standardized uptake values. If focal anal uptake is observed, the recommendation of colonofibroscopy is needed.