RT Journal Article
SR Electronic
T1 Pre-clinical evaluation of a respiratory motion correction technique in dual gated cardiac imaging
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1470
OP 1470
VO 50
IS supplement 2
A1 Frederic Lamare
A1 Ornella Rimoldi
A1 Mika Teras
A1 Tommi Kokki
A1 Juhani Knuuti
A1 Dimitris Visvikis
A1 Paolo Camici
YR 2009
UL http://jnm.snmjournals.org/content/50/supplement_2/1470.abstract
AB 1470 Objectives Cardiac imaging suffers from respiratory and cardiac motion. Although double gated acquisition may lead to both respiratory and cardiac motion compensation, the gated images are of poor quality as a result of using only part of the acquired data. The objectives of this work were to find out the optimum fashion of combining binned data and the most appropriate motion model in order to define the best acquisition mode to reconstruct a motion free cardiac image. Methods 4 preclinical cases were used in this evaluation. A GE Discovery RX PET/CT system was used to acquire PET data in list mode (LM). Respiratory and cardiac triggers were registered within the LM file using an RPM and an ECG device. Data were binned considering 4 cardiac gates (1-3 in the systole and 4 in the diastole) in combination with a variable number of respiratory gates. The gated images were subsequently used in combination with an affine and an elastic registration algorithm to derive transformation parameters subsequently integrated during the reconstruction to produce a motion free cardiac image. Results Superior contrast was seen in the corrected images using the affine/elastic models and the diastolic phase in comparison to the use of the complete cardiac cycle. However, the reduction of the SNR observed when using only the diastolic phase is not seen when an elastic model is used allowing the combination of all cardiac gated bins. 3 respiratory bins seem to be adequate for both motion correction models used. Conclusions Although an affine model is adequate to correct for respiratory motion only, when trying to compensate for both cardiac beating and respiration, the elastic model appears more appropriate.