RT Journal Article
SR Electronic
T1 Detector system for a positron emission mammography/tomography (PEM/PET) breast biopsy device
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 186P
OP 186P
VO 47
IS suppl 1
A1 Raylman, Raymond
A1 Majewski, Stan
A1 Smith, Mark
A1 Kross, Brian
A1 Popov, Vladimir
A1 Proffitt, James
A1 Hammond, William
A1 Weisenberger, Andrew
A1 Wojcik, Randy
A1 Kinahan, Paul
YR 2006
UL http://jnm.snmjournals.org/content/47/suppl_1/186P.2.abstract
AB 534 Objectives: Tomographic breast imaging systems can potentially improve the detection and diagnosis of cancer in women with radiodense and/or fibrocystic breasts. Our group is developing a high-resolution positron emission mammography and tomography biopsy device (called PEM/PET) to guide the biopsy of suspicious breast lesions utilizing the breast PET images, and then verify the position of the biopsy needle prior to tissue acquisition with limited-angle PEM imaging. Methods: The PEM/PET scanner consists of two sets of rotating planar detector heads mounted on a gantry located beneath the patient bed. The detector heads are a combination of flat panel position-sensitive photomultipliers (PSPMTs) and pixelated scintillator arrays. Each scintillator array consists of a 96×72 array of 2×2×15mm^3 LYSO detector elements (pitch= 2.1mm). These arrays are coupled to a 4×3 array of Hamamatsu H8500 PSPMTs. The field-of-view of the system is 20×15cm^2. Results: Measurements from the prototype detector units yielded an average light spread function and energy resolution over the field-of-view of ~2.3mm FWHM and 25% FWHM, respectively, utilizing F-18 point-like sources. Tests were also performed on a new, fast FPGA-based data acquisition readout developed specifically for this project to replace the current slower VME-based PEM/PET readout system. Detector element separation obtained with this readout was excellent (~3:1 maximum peak-to-valley ratio), allowing all scintillator pixels to be identified. Conclusions: The successful, initial testing of the PEM/PET detector system indicates that the imaging capabilities of the imager will be excellent. Phantom testing of the system will begin shortly. The addition of a CT scanner to the gantry to create a dual-modality imager/biopsy apparatus is also planned. Research Support (if any): This work was supported by the National Cancer Institute (Grant Number R01 CA094196) and by the Thomas Jefferson National Accelerator Facility. The Southeastern Universities Research Association operates the Thomas Jefferson National Accelerator Facility for the United States Department of Biological and Environmental Research of the Office of Science of the U.S. Department of Energy under contract DE-AC05-84ER40150.