PT  - JOURNAL ARTICLE
AU  - Yuni K. Dewaraja
AU  - Michael Ljungberg
AU  - Alan J. Green
AU  - Pat B. Zanzonico
AU  - Eric C. Frey
AU  - SNMMI MIRD Committee
AU  - Wesley E. Bolch
AU  - A. Bertrand Brill
AU  - Mark Dunphy
AU  - Darrell R. Fisher
AU  - Roger W. Howell
AU  - Ruby F. Meredith
AU  - George Sgouros
AU  - Barry W. Wessels
TI  - MIRD Pamphlet No. 24: Guidelines for Quantitative <sup>131</sup>I SPECT in Dosimetry Applications
AID  - 10.2967/jnumed.113.122390
DP  - 2013 Dec 01
TA  - Journal of Nuclear Medicine
PG  - 2182--2188
VI  - 54
IP  - 12
4099  - http://jnm.snmjournals.org/content/54/12/2182.short
4100  - http://jnm.snmjournals.org/content/54/12/2182.full
SO  - J Nucl Med2013 Dec 01; 54
AB  - The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotope-specific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, 131I. The purpose of this document is to provide guidance on the development of protocols for quantitative 131I SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry.