RT Journal Article SR Electronic T1 V/Q Scanning Using SPECT and SPECT/CT JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1588 OP 1596 DO 10.2967/jnumed.113.124602 VO 54 IS 9 A1 Roach, Paul J. A1 Schembri, Geoffrey P. A1 Bailey, Dale L. YR 2013 UL http://jnm.snmjournals.org/content/54/9/1588.abstract AB Planar ventilation–perfusion (V/Q) scanning is often used to investigate pulmonary embolism; however, it has well-recognized limitations. SPECT overcomes many of these through its ability to generate 3-dimensional imaging data. V/Q SPECT has higher sensitivity, specificity, and accuracy than planar imaging and a lower indeterminate rate. SPECT allows for new ways to display and analyze data, such as parametric V/Q ratio images. Compared with CT pulmonary angiography, SPECT has higher sensitivity, a lower radiation dose, fewer technically suboptimal studies, and no contrast-related complications. Any nuclear medicine department equipped with a modern hybrid scanner can now perform combined V/Q SPECT with CT (using low-dose protocols) to further enhance diagnostic accuracy. V/Q SPECT (with or without CT) has application in other pulmonary conditions and in research.