PT  - JOURNAL ARTICLE
AU  - Paul J. Roach
AU  - Geoffrey P. Schembri
AU  - Dale L. Bailey
TI  - V/Q Scanning Using SPECT and SPECT/CT
AID  - 10.2967/jnumed.113.124602
DP  - 2013 Sep 01
TA  - Journal of Nuclear Medicine
PG  - 1588--1596
VI  - 54
IP  - 9
4099  - http://jnm.snmjournals.org/content/54/9/1588.short
4100  - http://jnm.snmjournals.org/content/54/9/1588.full
SO  - J Nucl Med2013 Sep 01; 54
AB  - Planar ventilation–perfusion (V/Q) scanning is often used to investigate pulmonary embolism; however, it has well-recognized limitations. SPECT overcomes many of these through its ability to generate 3-dimensional imaging data. V/Q SPECT has higher sensitivity, specificity, and accuracy than planar imaging and a lower indeterminate rate. SPECT allows for new ways to display and analyze data, such as parametric V/Q ratio images. Compared with CT pulmonary angiography, SPECT has higher sensitivity, a lower radiation dose, fewer technically suboptimal studies, and no contrast-related complications. Any nuclear medicine department equipped with a modern hybrid scanner can now perform combined V/Q SPECT with CT (using low-dose protocols) to further enhance diagnostic accuracy. V/Q SPECT (with or without CT) has application in other pulmonary conditions and in research.