RT Journal Article
SR Electronic
T1 Enriching the Interventional Vision of Cancer with Fluorescence and Optoacoustic Imaging
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 664
OP 667
DO 10.2967/jnumed.111.099796
VO 54
IS 5
A1 P. Beatriz Garcia-Allende
A1 Jürgen Glatz
A1 Maximilian Koch
A1 Vasilis Ntziachristos
YR 2013
UL http://jnm.snmjournals.org/content/54/5/664.abstract
AB Among several techniques considered for surgical and endoscopic imaging, novel optical methods are evolving as a promising approach for interventional guidance. Pilot clinical applications of fluorescence molecular imaging have demonstrated the benefits of using targeted fluorescent agents in cancer surgery. This premise can be extended broadly to interventional guidance through an increasing number of targeted agents and detection techniques. Beyond epi-illumination fluorescence imaging, optoacoustic (photoacoustic) methods are emerging to offer high-resolution cross-sectional optical imaging through several millimeters to centimeters of depth. We present an overview of key recent developments in optical interventional imaging and outline the potential for a paradigm shift in surgical and endoscopic visualization.