RT Journal Article
SR Electronic
T1 In Vivo Tracking Techniques for Cellular Regeneration, Replacement, and Redirection
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 1825
OP 1828
DO 10.2967/jnumed.112.106146
VO 53
IS 12
A1 Aarntzen, Erik H.J.G.
A1 Srinivas, Mangala
A1 Walczak, Piotr
A1 Janowski, Miroslaw
A1 Heerschap, Arend
A1 de Vries, I. Jolanda M.
A1 Figdor, Carl G.
A1 Bulte, Jeff W.M.
A1 Oyen, Wim J.G.
YR 2012
UL http://jnm.snmjournals.org/content/53/12/1825.abstract
AB Cellular therapy can be defined as the transplantation of living cells for the treatment of medical conditions. Three main objectives of cellular therapy are regeneration of damaged tissue, replacement of function by secretion of biologically active molecules, and redirection of aberrant processes. Given the complex nature of these approaches, in vivo tracking of the transplanted cells is critical to evaluate their potential benefit and to optimize treatment strategies. Recent advances are reviewed that enable in vivo cell tracking as an important adjunct to implement cellular therapy in clinical practice.