RT Journal Article
SR Electronic
T1 The Vascular Biology of Atherosclerosis and Imaging Targets
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 33S
OP 37S
DO 10.2967/jnumed.109.069633
VO 51
IS Supplement 1
A1 Peter Libby
A1 Marcelo DiCarli
A1 Ralph Weissleder
YR 2010
UL http://jnm.snmjournals.org/content/51/Supplement_1/33S.abstract
AB The growing worldwide health challenge of atherosclerosis, together with advances in imaging technologies, have stimulated considerable interest in novel approaches to gauging this disease. The last several decades have witnessed a burgeoning in understanding of the molecular pathways involved in atherogenesis, lesion progression, and the mechanisms underlying the complications of human atherosclerotic plaques. The imaging of atherosclerosis is reaching beyond anatomy to encompass assessment of aspects of plaque biology related to the pathogenesis and complication of the disease. The harnessing of these biologic insights promises to provide a plethora of new targets for molecular imaging of atherosclerosis. The goals for the years to come must include translation of the experimental work to visualization of these appealing biologic targets in humans.