PT  - JOURNAL ARTICLE
AU  - Libby, Peter
AU  - DiCarli, Marcelo
AU  - Weissleder, Ralph
TI  - The Vascular Biology of Atherosclerosis and Imaging Targets
AID  - 10.2967/jnumed.109.069633
DP  - 2010 May 01
TA  - Journal of Nuclear Medicine
PG  - 33S--37S
VI  - 51
IP  - Supplement 1
4099  - http://jnm.snmjournals.org/content/51/Supplement_1/33S.short
4100  - http://jnm.snmjournals.org/content/51/Supplement_1/33S.full
SO  - J Nucl Med2010 May 01; 51
AB  - The growing worldwide health challenge of atherosclerosis, together with advances in imaging technologies, have stimulated considerable interest in novel approaches to gauging this disease. The last several decades have witnessed a burgeoning in understanding of the molecular pathways involved in atherogenesis, lesion progression, and the mechanisms underlying the complications of human atherosclerotic plaques. The imaging of atherosclerosis is reaching beyond anatomy to encompass assessment of aspects of plaque biology related to the pathogenesis and complication of the disease. The harnessing of these biologic insights promises to provide a plethora of new targets for molecular imaging of atherosclerosis. The goals for the years to come must include translation of the experimental work to visualization of these appealing biologic targets in humans.