RT Journal Article
SR Electronic
T1 Challenges in the Translation of Cardiovascular Cell Therapy
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 122S
OP 127S
DO 10.2967/jnumed.109.068304
VO 51
IS Supplement 1
A1 Gupta, Rajesh
A1 Losordo, Douglas W.
YR 2010
UL http://jnm.snmjournals.org/content/51/Supplement_1/122S.abstract
AB Ischemic cardiovascular diseases cause a significant burden of morbidity and mortality throughout the world. Over the past decade, we have learned a tremendous amount about the biology of various stem and progenitor cells. Multiple preclinical experiments have demonstrated significant bioactivity in a wide variety of stem and progenitor cells. Early clinical trials have also shown some promising results. This review will focus on the current challenges in the translation of cell therapy to a viable clinical therapy. Additionally, we will highlight the role of cardiovascular imaging and molecular imaging in the future of stem cell therapy.