RT Journal Article SR Electronic T1 Influence of Bowel Preparation Before 18F-FDG PET/CT on Physiologic 18F-FDG Activity in the Intestine JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 507 OP 510 DO 10.2967/jnumed.109.071001 VO 51 IS 4 A1 Jan D. Soyka A1 Klaus Strobel A1 Patrick Veit-Haibach A1 Niklaus G. Schaefer A1 Daniel T. Schmid A1 Alois Tschopp A1 Thomas F. Hany YR 2010 UL http://jnm.snmjournals.org/content/51/4/507.abstract AB Our objective was to investigate the use of bowel preparation before 18F-FDG PET/CT to reduce intestinal 18F-FDG uptake. Methods: Sixty-five patients with abdominal neoplasias were assigned either to a bowel-preparation group (n = 26) or to a native group (n = 39). 18F-FDG activity was measured in the small intestine and the colon. Results: In the 26 patients with bowel preparation, average maximal standardized uptake value (SUVmax) was 3.5 in the small intestine and 4.4 in the colon. In the 39 patients without bowel preparation, average SUVmax was 2.6 in the small intestine and 2.7 in the colon. 18F-FDG activity impaired diagnosis in 6 patients (23%) in the bowel-preparation group and 11 patients (28%) in the native group (P = 0.5). SUVmax in the colon was significantly higher in the bowel-preparation group (P = 0.002), but SUVmax in the small intestine did not significantly differ between the 2 groups (P = 0.088). Conclusion: Bowel preparation increases 18F-FDG activity in the large intestine and is therefore not useful before PET/CT.