RT Journal Article
SR Electronic
T1 Influence of Bowel Preparation Before 18F-FDG PET/CT on Physiologic 18F-FDG Activity in the Intestine
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 507
OP 510
DO 10.2967/jnumed.109.071001
VO 51
IS 4
A1 Jan D. Soyka
A1 Klaus Strobel
A1 Patrick Veit-Haibach
A1 Niklaus G. Schaefer
A1 Daniel T. Schmid
A1 Alois Tschopp
A1 Thomas F. Hany
YR 2010
UL http://jnm.snmjournals.org/content/51/4/507.abstract
AB Our objective was to investigate the use of bowel preparation before 18F-FDG PET/CT to reduce intestinal 18F-FDG uptake. Methods: Sixty-five patients with abdominal neoplasias were assigned either to a bowel-preparation group (n = 26) or to a native group (n = 39). 18F-FDG activity was measured in the small intestine and the colon. Results: In the 26 patients with bowel preparation, average maximal standardized uptake value (SUVmax) was 3.5 in the small intestine and 4.4 in the colon. In the 39 patients without bowel preparation, average SUVmax was 2.6 in the small intestine and 2.7 in the colon. 18F-FDG activity impaired diagnosis in 6 patients (23%) in the bowel-preparation group and 11 patients (28%) in the native group (P = 0.5). SUVmax in the colon was significantly higher in the bowel-preparation group (P = 0.002), but SUVmax in the small intestine did not significantly differ between the 2 groups (P = 0.088). Conclusion: Bowel preparation increases 18F-FDG activity in the large intestine and is therefore not useful before PET/CT.