TY - JOUR T1 - <sup>68</sup>Ga-Citrate PET/CT for Evaluating Patients with Infections of the Bone: Preliminary Results JF - Journal of Nuclear Medicine JO - J Nucl Med SP - 1932 LP - 1936 DO - 10.2967/jnumed.110.080184 VL - 51 IS - 12 AU - Cristina Nanni AU - Costantino Errani AU - Luca Boriani AU - Lorenzo Fantini AU - Valentina Ambrosini AU - Stefano Boschi AU - Domenico Rubello AU - Cinzia Pettinato AU - Mario Mercuri AU - Alessandro Gasbarrini AU - Stefano Fanti Y1 - 2010/12/01 UR - http://jnm.snmjournals.org/content/51/12/1932.abstract N2 - The aim of this work was to preliminarily evaluate the sensitivity, specificity, positive predictive value, negative predictive value, and overall accuracy of 68Ga-citrate PET/CT in a population of patients with suspected bone infections. Methods: We enrolled 31 patients with suspected osteomyelitis or diskitis who underwent a total of forty 68Ga-citrate PET/CT scans. The results were compared with different combinations of diagnostic procedures (MRI, radiography, CT, or white blood cell scintigraphy), biopsy (when diagnostic), and follow-up data (at least 1 y) to determine the performance of 68Ga-citrate PET/CT. Results: We found a sensitivity of 100%, a specificity of 76%, a positive predictive value of 85%, a negative predictive value of 100%, and an overall accuracy of 90%. Conclusion: Although preliminary, these data confirm a possible role for 68Ga-citrate in the diagnosis of bone infections, especially in consideration of its favorable characteristics. ER -