PT - JOURNAL ARTICLE AU - Czernin, Johannes AU - Satyamurthy, Nagichettiar AU - Schiepers, Christiaan TI - Molecular Mechanisms of Bone <sup>18</sup>F-NaF Deposition AID - 10.2967/jnumed.110.077933 DP - 2010 Dec 01 TA - Journal of Nuclear Medicine PG - 1826--1829 VI - 51 IP - 12 4099 - http://jnm.snmjournals.org/content/51/12/1826.short 4100 - http://jnm.snmjournals.org/content/51/12/1826.full SO - J Nucl Med2010 Dec 01; 51 AB - There is renewed interest in 18F-NaF bone imaging with PET or PET/CT. The current brief discussion focuses on the molecular mechanisms of 18F-NaF deposition in bone and presents model-based approaches to quantifying bone perfusion and metabolism in the context of preclinical and clinical applications of bone imaging with PET.