RT Journal Article SR Electronic T1 Complementary Roles of Whole-Body Diffusion-Weighted MRI and 18F-FDG PET: The State of the Art and Potential Applications JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1549 OP 1558 DO 10.2967/jnumed.109.073908 VO 51 IS 10 A1 Thomas C. Kwee A1 Taro Takahara A1 Reiji Ochiai A1 Dow-Mu Koh A1 Yoshiharu Ohno A1 Katsuyuki Nakanishi A1 Tetsu Niwa A1 Thomas L. Chenevert A1 Peter R. Luijten A1 Abass Alavi YR 2010 UL http://jnm.snmjournals.org/content/51/10/1549.abstract AB 18F-FDG PET is an established functional imaging modality for the evaluation of human disease. Diffusion-weighted MRI (DWI) is another rapidly evolving functional imaging modality that can be used to evaluate oncologic and nononcologic lesions throughout the body. The information provided by 18F-FDG PET and DWI can be complementary, because the 2 methods are based on completely different biophysical underpinnings. This article will describe the basic principles, clinical applications, and limitations of DWI. In addition, the available evidence that correlates and compares 18F-FDG PET and DWI will be reviewed.