PT  - JOURNAL ARTICLE
AU  - Kwee, Thomas C.
AU  - Takahara, Taro
AU  - Ochiai, Reiji
AU  - Koh, Dow-Mu
AU  - Ohno, Yoshiharu
AU  - Nakanishi, Katsuyuki
AU  - Niwa, Tetsu
AU  - Chenevert, Thomas L.
AU  - Luijten, Peter R.
AU  - Alavi, Abass
TI  - Complementary Roles of Whole-Body Diffusion-Weighted MRI and <sup>18</sup>F-FDG PET: The State of the Art and Potential Applications
AID  - 10.2967/jnumed.109.073908
DP  - 2010 Oct 01
TA  - Journal of Nuclear Medicine
PG  - 1549--1558
VI  - 51
IP  - 10
4099  - http://jnm.snmjournals.org/content/51/10/1549.short
4100  - http://jnm.snmjournals.org/content/51/10/1549.full
SO  - J Nucl Med2010 Oct 01; 51
AB  - 18F-FDG PET is an established functional imaging modality for the evaluation of human disease. Diffusion-weighted MRI (DWI) is another rapidly evolving functional imaging modality that can be used to evaluate oncologic and nononcologic lesions throughout the body. The information provided by 18F-FDG PET and DWI can be complementary, because the 2 methods are based on completely different biophysical underpinnings. This article will describe the basic principles, clinical applications, and limitations of DWI. In addition, the available evidence that correlates and compares 18F-FDG PET and DWI will be reviewed.