PT  - JOURNAL ARTICLE
AU  - Zang-Hee Cho
AU  - Young-Don Son
AU  - Hang-Keun Kim
AU  - Sung-Tae Kim
AU  - Sang-Yoon Lee
AU  - Je-Geun Chi
AU  - Chan-Woong Park
AU  - Young-Bo Kim
TI  - Substructural Hippocampal Glucose Metabolism Observed on PET/MRI
AID  - 10.2967/jnumed.110.076182
DP  - 2010 Oct 01
TA  - Journal of Nuclear Medicine
PG  - 1545--1548
VI  - 51
IP  - 10
4099  - http://jnm.snmjournals.org/content/51/10/1545.short
4100  - http://jnm.snmjournals.org/content/51/10/1545.full
SO  - J Nucl Med2010 Oct 01; 51
AB  - The hippocampus is one of the best-known neural structures in the brain and has been of interest in observing the substructures and their metabolic functions. However, it has been difficult to distinguish its substructures and functions in vivo because of its small size. Methods: 18F-FDG PET and high-resolution MRI of the hippocampus were performed on 5 healthy subjects using a PET/MRI system. The metabolism of each hippocampal substructure was measured in vivo on the basis of the MR images. Results: The dentate gyrus and cornu ammonis 4 showed the highest glucose uptake in the healthy subjects. Conclusion: Measuring glucose metabolism in the substructures of the hippocampus could provide a new tool for the future investigation of related brain diseases or functional studies, such as Alzheimer disease or memory and learning studies.