RT Journal Article SR Electronic T1 Role of 18F-FDG PET in Assessment of Response in Non–Small Cell Lung Cancer JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 31S OP 42S DO 10.2967/jnumed.108.057216 VO 50 IS Suppl 1 A1 Rodney J. Hicks YR 2009 UL http://jnm.snmjournals.org/content/50/Suppl_1/31S.abstract AB Despite recognized limitations, structural imaging with CT remains the standard technique for evaluating the response of lung cancer to both chemotherapy and radiotherapy. This evaluation has become increasingly important with the advent of neoadjuvant therapy before surgery. The high uptake of 18F-FDG in most lung cancers and the demonstration that successful treatment reduces uptake have led to increasing enthusiasm for the use of PET and PET/CT to assess the therapeutic response. In this review, theoretic considerations and current evidence supporting the role of 18F-FDG PET are discussed.