PT  - JOURNAL ARTICLE
AU  - Hicks, Rodney J.
TI  - Role of <sup>18</sup>F-FDG PET in Assessment of Response in Non–Small Cell Lung Cancer
AID  - 10.2967/jnumed.108.057216
DP  - 2009 May 01
TA  - Journal of Nuclear Medicine
PG  - 31S--42S
VI  - 50
IP  - Suppl 1
4099  - http://jnm.snmjournals.org/content/50/Suppl_1/31S.short
4100  - http://jnm.snmjournals.org/content/50/Suppl_1/31S.full
SO  - J Nucl Med2009 May 01; 50
AB  - Despite recognized limitations, structural imaging with CT remains the standard technique for evaluating the response of lung cancer to both chemotherapy and radiotherapy. This evaluation has become increasingly important with the advent of neoadjuvant therapy before surgery. The high uptake of 18F-FDG in most lung cancers and the demonstration that successful treatment reduces uptake have led to increasing enthusiasm for the use of PET and PET/CT to assess the therapeutic response. In this review, theoretic considerations and current evidence supporting the role of 18F-FDG PET are discussed.