RT Journal Article
SR Electronic
T1 Identification of a Shine-Through Artifact in the Trachea with <sup>124</sup>I PET/CT
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 909
OP 911
DO 10.2967/jnumed.108.060442
VO 50
IS 6
A1 Abdul-Fatah, Sakar B.
A1 Zamburlini, Mariangela
A1 Halders, Servé G.E.A.
A1 Brans, Boudewijn
A1 Teule, Gerrit J.J.
A1 Kemerink, Gerrit J.
YR 2009
UL http://jnm.snmjournals.org/content/50/6/909.abstract
AB The presence of 124I in tissue near the trachea can cause a phenomenon that might be called shine-through. The effect is due to high-energy positrons that cross the air-filled trachea and annihilate at the opposite tracheal wall, incorrectly suggesting uptake at that location. Methods: We investigated shine-through using 124I, 68Ga, and 18F PET/CT scans of a neck phantom. Additionally, we evaluated 124I studies of 29 patients with differentiated thyroid cancer who underwent imaging for postsurgical staging. Results: In the phantom studies with a 0.1-mL 124I source, the relative intensity of shine-through decreased from 7% to nearly zero when the thickness of the positron-stopping layer was increased from 0.3 to 3.85 mm. In patients, shine-through was observed in 5 of the 29 studies, with intensities between 0.7% and 14%. Conclusion: Shine-through appears rather common in differentiated thyroid cancer. Recognition is important for identification of real lesions, calculation of uptake, and dosimetry.