RT Journal Article SR Electronic T1 Comparison of 18F-FDG PET and MRI in Assessment of Uterine Smooth Muscle Tumors JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 708 OP 712 DO 10.2967/jnumed.107.047142 VO 49 IS 5 A1 Yoshio Yoshida A1 Tetsuji Kurokawa A1 Yoko Sawamura A1 Akiko Shinagawa A1 Tetsuya Tsujikawa A1 Hidehiko Okazawa A1 Tatsuro Tsuchida A1 Yoshiaki Imamura A1 Narufumi Suganuma A1 Fumikazu Kotsuji YR 2008 UL http://jnm.snmjournals.org/content/49/5/708.abstract AB The purpose of this study was to prospectively determine whether combined MRI and 18F-FDG PET is more accurate than MRI in assessing nonbenign uterine smooth muscle tumors (USMTs). Methods: Seventy patients (mean age, 49 ± 10 y; range, 28–77 y) suspected of having nonbenign USMTs underwent both MRI and 18F-FDG PET before surgery. Results were evaluated using receiver-operating-characteristic (ROC) analyses and the Cochran Q test. Results: The area under the ROC curve for MRI with 18F-FDG PET was significantly higher than that for MRI (0.97 vs. 0.89, P < 0.05). Although multiple comparisons using the Cochran Q test were not significant, the sensitivity, specificity, and accuracy for MRI with 18F-FDG PET with probable nonbenign USMT cases considered to be positive were higher than those for MRI (93.3% vs. 73.3%; 92.7% vs. 85.5%; and 92.9% vs. 82.9%, respectively). Conclusion: MRI with 18F-FDG PET is useful in assessing nonbenign USMTs, as compared with MRI.