PT - JOURNAL ARTICLE AU - Yoshio Yoshida AU - Tetsuji Kurokawa AU - Yoko Sawamura AU - Akiko Shinagawa AU - Tetsuya Tsujikawa AU - Hidehiko Okazawa AU - Tatsuro Tsuchida AU - Yoshiaki Imamura AU - Narufumi Suganuma AU - Fumikazu Kotsuji TI - Comparison of <sup>18</sup>F-FDG PET and MRI in Assessment of Uterine Smooth Muscle Tumors AID - 10.2967/jnumed.107.047142 DP - 2008 May 01 TA - Journal of Nuclear Medicine PG - 708--712 VI - 49 IP - 5 4099 - http://jnm.snmjournals.org/content/49/5/708.short 4100 - http://jnm.snmjournals.org/content/49/5/708.full SO - J Nucl Med2008 May 01; 49 AB - The purpose of this study was to prospectively determine whether combined MRI and 18F-FDG PET is more accurate than MRI in assessing nonbenign uterine smooth muscle tumors (USMTs). Methods: Seventy patients (mean age, 49 ± 10 y; range, 28–77 y) suspected of having nonbenign USMTs underwent both MRI and 18F-FDG PET before surgery. Results were evaluated using receiver-operating-characteristic (ROC) analyses and the Cochran Q test. Results: The area under the ROC curve for MRI with 18F-FDG PET was significantly higher than that for MRI (0.97 vs. 0.89, P &lt; 0.05). Although multiple comparisons using the Cochran Q test were not significant, the sensitivity, specificity, and accuracy for MRI with 18F-FDG PET with probable nonbenign USMT cases considered to be positive were higher than those for MRI (93.3% vs. 73.3%; 92.7% vs. 85.5%; and 92.9% vs. 82.9%, respectively). Conclusion: MRI with 18F-FDG PET is useful in assessing nonbenign USMTs, as compared with MRI.