RT Journal Article
SR Electronic
T1 Latest Advances in Molecular Imaging Instrumentation
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 5S
OP 23S
DO 10.2967/jnumed.108.045880
VO 49
IS Suppl 2
A1 Bernd J. Pichler
A1 Hans F. Wehrl
A1 Martin S. Judenhofer
YR 2008
UL http://jnm.snmjournals.org/content/49/Suppl_2/5S.abstract
AB This review concentrates on the latest advances in molecular imaging technology, including PET, MRI, and optical imaging. In PET, significant improvements in tumor detection and image resolution have been achieved by introducing new scintillation materials, iterative image reconstruction, and correction methods. These advances enabled the first clinical scanners capable of time-of-flight detection and incorporating point-spread-function reconstruction to compensate for depth-of-interaction effects. In the field of MRI, the most important developments in recent years have mainly been MRI systems with higher field strengths and improved radiofrequency coil technology. Hyperpolarized imaging, functional MRI, and MR spectroscopy provide molecular information in vivo. A special focus of this review article is multimodality imaging and, in particular, the emerging field of combined PET/MRI.