RT Journal Article SR Electronic T1 High 18F-FDG Uptake in Synthetic Aortic Vascular Grafts on PET/CT in Symptomatic and Asymptomatic Patients JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1601 OP 1605 DO 10.2967/jnumed.108.053462 VO 49 IS 10 A1 Johan Wassélius A1 Jonas Malmstedt A1 Bo Kalin A1 Stig Larsson A1 Anders Sundin A1 Ulf Hedin A1 Hans Jacobsson YR 2008 UL http://jnm.snmjournals.org/content/49/10/1601.abstract AB Graft infection is a serious complication to vascular surgery. The aim of this study was to assess 18F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection. Methods: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for 18F-FDG accumulation. Clinical and biochemical data were obtained from patient records. Results: High 18F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation. Conclusion: 18F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by 18F-FDG PET/CT is evident.