PT - JOURNAL ARTICLE AU - Johan Wassélius AU - Jonas Malmstedt AU - Bo Kalin AU - Stig Larsson AU - Anders Sundin AU - Ulf Hedin AU - Hans Jacobsson TI - High <sup>18</sup>F-FDG Uptake in Synthetic Aortic Vascular Grafts on PET/CT in Symptomatic and Asymptomatic Patients AID - 10.2967/jnumed.108.053462 DP - 2008 Oct 01 TA - Journal of Nuclear Medicine PG - 1601--1605 VI - 49 IP - 10 4099 - http://jnm.snmjournals.org/content/49/10/1601.short 4100 - http://jnm.snmjournals.org/content/49/10/1601.full SO - J Nucl Med2008 Oct 01; 49 AB - Graft infection is a serious complication to vascular surgery. The aim of this study was to assess 18F-FDG uptake in vascular grafts in patients with or without symptoms of graft infection. Methods: In all 2,045 patients examined by PET/CT at our clinic, 16 patients with synthetic aortic grafts were identified and reevaluated for 18F-FDG accumulation. Clinical and biochemical data were obtained from patient records. Results: High 18F-FDG uptake was found in 10 of 12 grafts in the patients who underwent open surgery and in 1 of 4 grafts in patients who underwent endovascular aneurysm repair. On the basis of biochemical and clinical data, it was concluded that 1 of the 16 patients had a graft infection at the time of investigation. Conclusion: 18F-FDG uptake in vascular grafts was found in the vast majority of patients without graft infection. The risk of a false-positive diagnosis of graft infection by 18F-FDG PET/CT is evident.