RT Journal Article
SR Electronic
T1 SPECT/Multislice Low-Dose CT: A Clinically Relevant Constituent in the Imaging Algorithm of Nononcologic Patients Referred for Bone Scintigraphy
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 319
OP 324
VO 48
IS 2
A1 Even-Sapir, Einat
A1 Flusser, Gideon
A1 Lerman, Hedva
A1 Lievshitz, Gennady
A1 Metser, Ur
YR 2007
UL http://jnm.snmjournals.org/content/48/2/319.abstract
AB The purpose of this prospective study was to assess the role of SPECT/multislice low-dose (Msl) CT as a constituent in the imaging algorithm of nononcologic patients referred for 99mTc-methylene diphosphonate bone scintigraphy (BS). Methods: SPECT/CT was performed using a novel hybrid system, which incorporates a γ-camera and a multislice low-dose CT, on 76 consecutive nononcologic patients with nonspecific scintigraphic findings, which required further correlation with morphologic data. Results: SPECT/MslCT was of added clinical value in 89% of the patients. Characterizing scintigraphic lesions by their morphologic appearance, SPECT/MslCT reached a final diagnosis in 49 of 85 (58%) nonspecific scintigraphic bone lesions found in 59% (45/76) of patients, obviating the need to perform additional imaging. In another 30% of patients (23/76), SPECT/MslCT data optimized the patients' imaging algorithm as the performance of a full-dose CT, MRI, or labeled-leukocyte scintigraphy as the next imaging was based on its findings combined with the patient's clinical presentation. Conclusion: SPECT/MslCT is a clinically relevant constituent in the imaging algorithm of nononcologic patients referred for BS.