TY - JOUR T1 - Dosimetry in Peptide Radionuclide Receptor Therapy: A Review JF - Journal of Nuclear Medicine JO - J Nucl Med SP - 1467 LP - 1475 VL - 47 IS - 9 AU - Marta Cremonesi AU - Mahila Ferrari AU - Lisa Bodei AU - Giampiero Tosi AU - Giovanni Paganelli Y1 - 2006/09/01 UR - http://jnm.snmjournals.org/content/47/9/1467.abstract N2 - The potential of targeted therapy with radiolabeled peptides has been reported in several clinical trials. Although there have been many improvements in dose estimation, a general and reliable dosimetric approach in peptide receptor radionuclide therapy (PRRT) is still a matter of debate. This article reviews the methods for PRRT dosimetry and the results presented in the literature. Radiopharmaceutical characteristics, data processing, dosimetric outcomes, and methods to protect critical organs are reported. The biological effective dose, based on the linear quadratic model, is also described. ER -