RT Journal Article SR Electronic T1 “Flying Through” and “Flying Around” a PET/CT Scan: Pilot Study and Development of 3D Integrated 18F-FDG PET/CT for Virtual Bronchoscopy and Colonoscopy JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1081 OP 1087 VO 47 IS 7 A1 Quon, Andrew A1 Napel, Sandy A1 Beaulieu, Christopher F. A1 Gambhir, Sanjiv S. YR 2006 UL http://jnm.snmjournals.org/content/47/7/1081.abstract AB The objective of this pilot project was to devise a new image acquisition and processing technique to produce PET/CT images rendered in 3-dimensional (3D) volume that can then be reviewed in several 3D formats such as virtual bronchoscopy and colonoscopy “fly-throughs” and external “fly-arounds.” Methods: We tested the new imaging and processing protocol on 24 patients with various malignancies to determine whether it could dependably acquire and reformat standard tomographic 2-dimensional PET/CT images into 3D renderings. Results: This new technique added helpful information to the diagnostic interpretation for 2 of the 24 patients. Further, in the 6 patients undergoing mediastinoscopy, bronchoscopy, or endoscopy, 3D imaging helped in preprocedural planning. Conclusion: In this initial study, we demonstrated both the feasibility of rendering PET/CT images into 3D volumes and the potential clinical utility of this technique for diagnostic lesion characterization and preprocedural planning.