RT Journal Article
SR Electronic
T1 The Promise of Immuno-PET in Radioimmunotherapy
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 164S
OP 171S
VO 46
IS 1 suppl
A1 Iris Verel
A1 Gerard W.M. Visser
A1 Guus A. van Dongen
YR 2005
UL http://jnm.snmjournals.org/content/46/1_suppl/164S.abstract
AB Immuno-PET as a quantitative imaging procedure before or concomitant with radioimmunotherapy is an attractive option to improve confirmation of tumor targeting and especially assessment of radiation dose delivery to both tumor and normal tissues. General information about PET, PET systems, and quantification is provided in this review. The requirements for an appropriate positron emitter and characteristics of the most attractive candidate emitters for immuno-PET are discussed. An overview of preclinical and clinical immuno-PET studies reported in the literature is provided.