RT Journal Article
SR Electronic
T1 New Automated Physical Phantom for Renography
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 495
OP 499
VO 45
IS 3
A1 Heikkinen, Jari O.
YR 2004
UL http://jnm.snmjournals.org/content/45/3/495.abstract
AB Physical phantoms have been used to test the diagnostic proficiency of nuclear medicine professionals and the accuracy of their equipment in external quality assurance surveys. No dynamic renal phantoms are commercially available. A new renal phantom, presented in this paper, was constructed and patented in the United States. Methods: The organs to be simulated by the phantom were in the form of containers filled with radioactive solution, and the device further comprised movable steel and lead plates between the containers and the γ-camera. The detectable radiation was regulated in accordance with automated computer-controlled step motors to move the attenuators to simulate a given patient situation. The reproducibility of the phantom measurements was defined as a coefficient of variation. Four different kidney-function simulations were repeated 3 times, and 6 parameters were compared. Results: The average root mean square deviation of the coefficient of variation was 6.7% for the perfusion integral, 1.3% for time to reach the maximum activity, 19.7% for mean transit time, 3.3% for function (Patlak [%]), 1.0% for outflow index (%), and 6.5% for time to reach the half-activity from maximum. Conclusion: With this phantom, the true values of most parameters measured are well known; it closely approaches true extraction, washout, and attenuation properties and curves, and the images produced are similar to those of patient studies. Compared with the first manual version, this new automated phantom is easy to use. Any desired clinical situation can be programmed. It is a promising tool for quality assurance and calibration of renography.