RT Journal Article
SR Electronic
T1 Comparison of Gated PET with MRI for Evaluation of Left Ventricular Function in Patients with Coronary Artery Disease
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 176
OP 182
VO 45
IS 2
A1 Riemer H.J.A. Slart
A1 Jeroen J. Bax
A1 Richard M. de Jong
A1 Jaep de Boer
A1 Hildo J. Lamb
A1 Piet H. Mook
A1 Antoon T.M. Willemsen
A1 Willem Vaalburg
A1 Dirk J. van Veldhuisen
A1 Pieter L. Jager
YR 2004
UL http://jnm.snmjournals.org/content/45/2/176.abstract
AB The aim of this study was to compare left ventricular (LV) volumes and regional wall motion determined by PET with those determined by the reference technique, cardiovascular MRI. Methods: LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), and LV ejection fraction (LVEF) were measured and regional wall motion was scored in 38 patients with chronic coronary artery disease by both gated 18F-FDG PET and MRI. A 9-segment model was used for PET and MRI to assess regional wall motion. Results: Good correlations were observed between MRI and gated PET for all parameters (r values ranging from 0.91 to 0.96). With PET, there was a significant but small underestimation of LVEDV and LVEF. Mean ± SD LVEDV, LVESV, and LVEF for MRI were 131 ± 57 mL, 91 ± 12 mL, and 33% ± 12%, respectively, and those for gated PET were 117 ± 56 mL, 85 ± 51 mL, and 30% ± 11%, respectively. For regional wall motion, an agreement of 85% was found, with a κ-statistic of 0.79 (95% confidence interval, 0.70–0.89; SE, 0.049). Conclusion: LV volumes, LVEF, and regional wall motion can be assessed with gated 18F-FDG PET and correlate well with these parameters assessed by MRI.