PT  - JOURNAL ARTICLE
AU  - Slart, Riemer H.J.A.
AU  - Bax, Jeroen J.
AU  - de Jong, Richard M.
AU  - de Boer, Jaep
AU  - Lamb, Hildo J.
AU  - Mook, Piet H.
AU  - Willemsen, Antoon T.M.
AU  - Vaalburg, Willem
AU  - van Veldhuisen, Dirk J.
AU  - Jager, Pieter L.
TI  - Comparison of Gated PET with MRI for Evaluation of Left Ventricular Function in Patients with Coronary Artery Disease
DP  - 2004 Feb 01
TA  - Journal of Nuclear Medicine
PG  - 176--182
VI  - 45
IP  - 2
4099  - http://jnm.snmjournals.org/content/45/2/176.short
4100  - http://jnm.snmjournals.org/content/45/2/176.full
SO  - J Nucl Med2004 Feb 01; 45
AB  - The aim of this study was to compare left ventricular (LV) volumes and regional wall motion determined by PET with those determined by the reference technique, cardiovascular MRI. Methods: LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), and LV ejection fraction (LVEF) were measured and regional wall motion was scored in 38 patients with chronic coronary artery disease by both gated 18F-FDG PET and MRI. A 9-segment model was used for PET and MRI to assess regional wall motion. Results: Good correlations were observed between MRI and gated PET for all parameters (r values ranging from 0.91 to 0.96). With PET, there was a significant but small underestimation of LVEDV and LVEF. Mean ± SD LVEDV, LVESV, and LVEF for MRI were 131 ± 57 mL, 91 ± 12 mL, and 33% ± 12%, respectively, and those for gated PET were 117 ± 56 mL, 85 ± 51 mL, and 30% ± 11%, respectively. For regional wall motion, an agreement of 85% was found, with a κ-statistic of 0.79 (95% confidence interval, 0.70–0.89; SE, 0.049). Conclusion: LV volumes, LVEF, and regional wall motion can be assessed with gated 18F-FDG PET and correlate well with these parameters assessed by MRI.