TY - JOUR T1 - The Role of Nuclear Medicine in the Prediction and Detection of Radiation-Associated Normal Pulmonary and Cardiac Damage JF - Journal of Nuclear Medicine JO - J Nucl Med SP - 1531 LP - 1539 VL - 44 IS - 9 AU - Ingeborg Goethals AU - Rudi Dierckx AU - Gert De Meerleer AU - Johan De Sutter AU - Olivier De Winter AU - Wilfried De Neve AU - Christophe Van de Wiele Y1 - 2003/09/01 UR - http://jnm.snmjournals.org/content/44/9/1531.abstract N2 - Dose–effect calculations used in the planning of modern radiotherapy (RT) involving normal lung or cardiac tissue rely on structural imaging techniques, such as CT, as the basis for measuring and predicting dose–response. However, more accurate methods for predicting dose–response may result if information on the locoregional functional status of the irradiated organ(s) is included in the computational model. For RT cases that involve delivering dose to the lung and heart, this may be achieved by the assessment of tomographic scintigraphies of lung perfusion (Q) and ventilation (V) and scintigraphic imaging of myocardial perfusion and function, respectively. ER -