RT Journal Article SR Electronic T1 Three-Dimensional Color-Modulated Display of Myocardial SPECT Perfusion Distributions Accurately Assesses Coronary Artery Disease JF Journal of Nuclear Medicine JO J Nucl Med FD Society of Nuclear Medicine SP 1941 OP 1946 VO 41 IS 12 A1 Cesar A. Santana A1 Ernest V. Garcia A1 Johnathan P. Vansant A1 Elizabeth G. Krawczynska A1 Russell D. Folks A1 C. David Cooke A1 Tracy L. Faber YR 2000 UL http://jnm.snmjournals.org/content/41/12/1941.abstract AB The objective of this study was to compare visual assessment of 3-dimensional color-modulated (to counts) surface displays with visual assessment of oblique tomographic slices of myocardial SPECT perfusion distributions in the detection and localization of coronary artery disease (CAD). Methods: Sixty-two consecutive patients (41 men, 21 women; mean age, 61 ± 11 y) who had undergone conventional dual-isotope perfusion SPECT were retrospectively chosen; 50 had undergone coronary arteriography previously, and 12 had less than a 5% likelihood of CAD. Four readers interpreted the 3-dimensional displays and slices in separate sessions while unaware of the findings of previous readings, the interpretations of others, and the angiographic results. The readers used a 5-point scoring system. Their average score was used for receiver operating characteristic (ROC) analysis. The area under the ROC curves was determined so that the ability of the 2 methods to detect and localize CAD could be compared. Results: No significant differences were found between visual interpretation of 3-dimensional displays and visual interpretation of slices. Conclusion: These preliminary results indicate that visual interpretation of 3-dimensional displays of myocardial perfusion SPECT distributions may someday replace visual assessment of conventional slices without loss of diagnostic accuracy.