RT Journal Article
SR Electronic
T1 Approaches to Imaging Immune Activation Using PET
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP jnumed.124.268289
DO 10.2967/jnumed.124.268289
A1 Parihar, Ashwin Singh
A1 Pant, Niharika
A1 Heidari, Pedram
A1 Fong, Lawrence
A1 Iravani, Amir
YR 2025
UL http://jnm.snmjournals.org/content/early/2025/04/30/jnumed.124.268289.abstract
AB This review explores the role of PET in imaging immune activation, particularly in oncology. 18F-FDG is widely used for assessing treatment response to immunotherapies and can demonstrate unique response patterns as well as immune-related adverse events. However, because of the limited specificity of 18F-FDG, newer PET radiopharmaceuticals targeting specific cellular or subcellular components of the immune system have been developed that can provide more precise information. The development of immune-specific PET radiopharmaceuticals offers significant potential for improving immune monitoring in both clinical practice and research.