PT - JOURNAL ARTICLE AU - Al-Ibraheem, Akram AU - Scott, Andrew M. AU - Abdlkadir, Ahmed Saad AU - Vrachimis, Alexis AU - Lamoureux, Francois AU - Trujillo, Patricia Bernal AU - Bailey, Dale L. AU - More, Stuart AU - Giammarile, Francesco AU - Kumar, Rakesh AU - Nonnekens, Julie AU - Cutler, Cathy S. AU - Urbain, Jean-Luc C. AU - Dibble, Elizabeth H. AU - Sathekge, Mike Machaba AU - Bomanji, Jamshed AU - Cerci, Juliano J. AU - Thomas, Elizabeth AU - Small, William AU - Louw, Lizette AU - O, Joo Hyun AU - Lee, Sze Ting AU - Nadel, Helen AU - Jacene, Heather AU - Watabe, Tadashi AU - Bom, Henry Hee-Seung AU - Bouyoucef, Salah Eddine AU - Weston, Charlotte AU - Wadsley, Jonathan AU - Irwin, Andy G. AU - Croasdale, Jilly AU - Zanzonico, Pat AU - Paez, Diana AU - Ghesani, Munir TI - Consensus Nomenclature for Radionuclide Therapy: Initial Recommendations from Nuclear Medicine Global Initiative AID - 10.2967/jnumed.124.269215 DP - 2025 May 01 TA - Journal of Nuclear Medicine PG - 757--763 VI - 66 IP - 5 4099 - http://jnm.snmjournals.org/content/66/5/757.short 4100 - http://jnm.snmjournals.org/content/66/5/757.full SO - J Nucl Med2025 May 01; 66 AB - Since its inception in 2012, the Nuclear Medicine Global Initiative (NMGI) of the Society of Nuclear Medicine and Molecular Imaging has played an important role in addressing significant challenges in the field of nuclear medicine and molecular imaging. The first 3 projects were dedicated to standardizing pediatric nuclear medicine practices, addressing the global challenges of radionuclide access and availability, and assessing the educational and training initiatives on theranostics across the globe. These efforts aimed to advance human health, foster worldwide educational collaboration, and standardize procedural guidelines to enhance quality and safety in nuclear medicine practice. In its latest project, NMGI aimed to develop a unified nomenclature for systemic radionuclide therapy in nuclear medicine, addressing the diverse terminology currently used. An online survey was distributed to NMGI member organizations, drawing participation from various geographical locations and disciplines. The survey anonymously collected responses from physicians, physicists, scientists, radiopharmacists, radiopharmaceutical scientists, dosimetrists, technologists, and nurse managers, totaling 240 responses from 30 countries. Findings revealed a prevailing use of the term targeted radionuclide therapy for radionuclide therapy, with 52% of respondents expressing a preference for this term. In contrast, approximately 37% favored “radiopharmaceutical therapy,” whereas 11% favored “molecular radionuclide therapy.” Other key terms under the umbrella of targeted radionuclide therapy were also discussed to achieve a consensus on terminology. NMGI efforts to standardize terminology in this dynamic and fluid field should improve communication within the field, better reflect the technology used, enable comparison of results, and ultimately lead to improved patient outcomes.