RT Journal Article
SR Electronic
T1 Dosimetry Software for Theranostic Applications: Current Capabilities and Future Prospects
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP jnumed.124.268998
DO 10.2967/jnumed.124.268998
A1 Kesner, Adam L.
A1 Brosch-Lenz, Julia
A1 Gear, Jonathan
A1 Lassmann, Michael
YR 2025
UL http://jnm.snmjournals.org/content/early/2025/01/07/jnumed.124.268998.abstract
AB Dosimetry is integral to informed implementation of radiopharmaceutical therapies, enabling personalized treatment planning and ensuring patient safety by calculating absorbed doses to organs and tumors. As the therapeutic radiopharmaceutical field continues to expand, dosimetry software has emerged as a crucial tool for optimization of treatment efficacy. This review discusses key features and capabilities that current dosimetry software solutions have or should have in the future. We highlight the need for standardization across platforms to support consistent and accurate dose calculations. Furthermore, we explore opportunities for advancing software, such as incorporating biologically effective dose modeling and improving uncertainty quantification. Looking ahead, we advocate for expanding infrastructure for open data sets and fostering ongoing collaboration between vendors and end users to guide the field toward greater integration and efficacy.