RT Journal Article
SR Electronic
T1 The Current and Future Roles of Precision Oncology in Advanced Breast Cancer
JF Journal of Nuclear Medicine
JO J Nucl Med
FD Society of Nuclear Medicine
SP 349
OP 356
DO 10.2967/jnumed.122.264882
VO 65
IS 3
A1 Jacene, Heather
A1 Dietsche, Eric
A1 Specht, Jennifer
YR 2024
UL http://jnm.snmjournals.org/content/65/3/349.abstract
AB Breast cancer is a common but heterogeneous disease characterized by several biologic features, including tumor grade, hormone receptor status, human epidermal growth factor receptor 2 status, and gene expression assays. These biologic and genomic features drive treatment decisions. In the advanced disease setting, inter- and intrapatient tumor heterogeneity is increasingly recognized as a challenge for optimizing treatment. Recent evidence and the recent approval of novel radiopharmaceuticals have increased recognition and acceptance of the potential of molecular imaging as a biomarker to impact and guide management decisions for advanced breast cancer.